Benzene

Benzene

SCHEMBL9548534

FC(F)(F)c1cscn1.c1ccccc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.40
AR P10275 2/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.35
GRM5 P41594 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
TRPV4 Q9HBA0 1/20 0.32
CA2 P00918 1/20 0.31
CHKA P35790 1/20 0.31
LMNA P02545 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
SCN9A Q15858 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299501 0.95
Methane SCHEMBL27580978 0.93 CYP19A1 (0.41) CYP19A1ARALDH1A1TSHRKDM4E
Propane SCHEMBL28860778 0.86 ALDH1A1 (0.39) CYP19A1ARALDH1A1TSHRTRPV4
SCHEMBL27939431 0.83 CYP19A1 (0.40) CYP19A1ARALDH1A1TSHRCA2
SCHEMBL31078346 0.77 CYP19A1 (0.46) CYP19A1ARALDH1A1TSHRKDM4E
SCHEMBL6247886 0.76 CYP19A1 (0.40) CYP19A1ARALDH1A1TSHRKDM4E
SCHEMBL29671539 0.76
Ethoxycarbonyl Group SCHEMBL27713053 0.73 LMNA (0.33) CYP19A1ARLMNA
SCHEMBL8684511 0.73 AR (0.52) CYP19A1ARALDH1A1TSHRKDM4E
SCHEMBL27817628 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5059025-A None JP disclosed
JP-H0559025-A DIARYLETHENE COMPOUND CENTRAL GLASS CO LTD 1993-03-09 JP disclosed