Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952092 | 0.95 | POLB (1.00) | POLBALDH1A1SMN1; SMN2TSHRFDPS | |
| SCHEMBL29951504 | 0.88 | ALDH1A1 (1.00) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL15332128 | 0.85 | ALDH1A1 (0.89) | POLBALDH1A1SMN1; SMN2TSHRFDPS | |
| SCHEMBL29951968 | 0.84 | POLB (0.73) | POLBALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL2559017 | 0.84 | ALDH1A1 (0.69) | POLBALDH1A1SMN1; SMN2TSHRFDPS | |
| SCHEMBL29958425 | 0.83 | ALDH1A1 (0.90) | POLBALDH1A1SMN1; SMN2TSHRFDPS | |
| SCHEMBL7677018 | 0.82 | ALDH1A1 (0.66) | POLBALDH1A1SMN1; SMN2TSHRFDPS | |
| SCHEMBL2556412 | 0.82 | ALDH1A1 (0.66) | POLBALDH1A1SMN1; SMN2TSHRFDPS | |
| SCHEMBL2557621 | 0.81 | ALDH1A1 (0.66) | POLBALDH1A1SMN1; SMN2TSHRFDPS | |
| SCHEMBL15332004 | 0.81 | ALDH1A1 (0.73) | POLBALDH1A1SMN1; SMN2TSHRFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |