Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950552 | 0.95 | POLB (0.90) | POLBALDH1A1SMN1; SMN2FDPSKDM4E | |
| SCHEMBL29951504 | 0.88 | ALDH1A1 (1.00) | POLBALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL2552984 | 0.85 | ALDH1A1 (1.00) | POLBALDH1A1SMN1; SMN2FDPSKDM4E | |
| SCHEMBL29951968 | 0.84 | POLB (0.73) | POLBALDH1A1SMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL29952641 | 0.83 | ALDH1A1 (1.00) | POLBALDH1A1SMN1; SMN2FDPSKDM4E | |
| SCHEMBL2562497 | 0.83 | ALDH1A1 (0.76) | POLBALDH1A1SMN1; SMN2FDPSKDM4E | |
| SCHEMBL2284391 | 0.82 | ALDH1A1 (0.74) | POLBALDH1A1SMN1; SMN2FDPSKDM4E | |
| SCHEMBL2562135 | 0.82 | ALDH1A1 (0.74) | POLBALDH1A1SMN1; SMN2FDPSKDM4E | |
| SCHEMBL15331508 | 0.81 | ALDH1A1 (0.81) | POLBALDH1A1SMN1; SMN2FDPSKDM4E | |
| SCHEMBL6536289 | 0.80 | POLB (0.74) | POLBALDH1A1SMN1; SMN2FDPSKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |