Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561777 | 0.89 | ALDH1A1 (0.60) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15332288 | 0.85 | ALDH1A1 (0.71) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29950552 | 0.84 | POLB (0.90) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29952092 | 0.84 | POLB (1.00) | POLBALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL29951504 | 0.83 | ALDH1A1 (1.00) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2556836 | 0.83 | ALDH1A1 (0.72) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2557610 | 0.82 | SMN1; SMN2 (0.71) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2559748 | 0.81 | SMN1; SMN2 (0.51) | POLBALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15330231 | 0.81 | ALDH1A1 (0.58) | POLBALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL16741108 | 0.80 | POLB (0.47) | POLBALDH1A1SMN1; SMN2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |