Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 3/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18485898 | 0.70 | RAB9A (0.54) | RAB9ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL15330712 | 0.70 | MAPT (0.54) | RAB9ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL795874 | 0.70 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2LMNAALDH1A1DHFR | |
| SCHEMBL8566977 | 0.70 | RAB9A (0.53) | RAB9ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL14869399 | 0.70 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2LMNAALDH1A1DHFR | |
| SCHEMBL18072476 | 0.69 | NUDT1 (0.57) | RAB9ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL21639536 | 0.69 | RAB9A (0.52) | RAB9ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL25691021 | 0.69 | ALDH1A1 (0.59) | RAB9ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL6261269 | 0.67 | RAB9A (0.50) | RAB9ASMN1; SMN2LMNAALDH1A1PDE4A | |
| SCHEMBL12227598 | 0.67 | RAB9A (0.50) | RAB9ASMN1; SMN2LMNAALDH1A1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |