Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514682 | 1.00 | ERN1 (0.46) | ERN1POLBMEN1KMT2APTPN1 | |
| SCHEMBL5749337 | 0.82 | ALDH1A1 (0.41) | ERN1POLBMEN1KMT2APTPN1 | |
| SCHEMBL4925716 | 0.79 | ALDH1A1 (0.44) | POLBMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL24184648 | 0.79 | ALDH1A1 (0.44) | POLBMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29521593 | 0.78 | DNMT1 (0.48) | ERN1POLBMEN1KMT2APTPN1 | |
| SCHEMBL7643518 | 0.78 | DNMT1 (0.48) | ERN1POLBMEN1KMT2APTPN1 | |
| SCHEMBL17704125 | 0.77 | MEN1 (0.41) | ERN1POLBMEN1KMT2APTPN1 | |
| SCHEMBL197337 | 0.77 | ERN1 (0.62) | ERN1POLBMEN1KMT2APTPN1 | |
| SCHEMBL31663413 | 0.77 | ERN1 (0.62) | ERN1POLBMEN1KMT2APTPN1 | |
| SCHEMBL320919 | 0.77 | ERN1 (0.47) | ERN1POLBMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |