Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521593 | 0.80 | DNMT1 (0.48) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL7643518 | 0.80 | DNMT1 (0.48) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL31663413 | 0.78 | ERN1 (0.62) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL197337 | 0.78 | ERN1 (0.62) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL950436 | 0.77 | POLB (0.50) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL28710839 | 0.77 | ERN1 (0.46) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL9431956 | 0.77 | ERN1 (0.46) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL514682 | 0.77 | ERN1 (0.46) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL2049662 | 0.77 | TSHR (0.54) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL29950700 | 0.77 | ERN1 (0.46) | ERN1POLBPTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | claimed |
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | disclosed |
| EP-1874893-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | UDC IRELAND LTD (IE) | 2016-05-25 | — | — | EP | disclosed |
| US-8092925-B2 | Organic electroluminescent device | FUJIFILM CORPORATION (JP) | 2012-01-10 | — | — | US | disclosed |
| US-7758971-B2 | Organic electroluminescent device | FUJIFILM CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7736755-B2 | Organic electroluminescent device | FUJIFILM CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20090039768-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-1874893-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Fujifilm Corporation (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-7199139-B2 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20060286406-A1 | Organic electroluminescent device | FUJI PHOTO FILM CO., LTD. | 2006-12-21 | — | — | US | disclosed |
| US-20060263632-A1 | High external quantum efficiency and excellent light emission efficiency; a metal complex of iridium or platinum having a tridentate or higher ligand | FUJI PHOTO FILM CO., LTD. | 2006-11-23 | — | — | US | disclosed |
| WO-2006115299-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2006-11-02 | — | — | WO | disclosed |
| EP-1354602-B1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | SANKYO CO (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-1695716-A2 | Medicinal compositions containing diuretics and insulin sensitizers | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2005-12-29 | — | — | US | disclosed |
| US-20040053974-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| EP-1354602-A1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | Sankyo Company, Limited (JP) | 2003-10-22 | — | — | EP | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053974-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | GPR119, INSR, IRS1 | ERN1 1151/4885POLB 4323/4885PTPN1 1429/4885 |
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | ERN1 2053/4885POLB 4097/4885PTPN1 610/4885 |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | GPR119, INSR, IRS1 | ERN1 1151/4885POLB 4323/4885PTPN1 1429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.