Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950700 | 0.82 | ERN1 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4CASP1 | |
| SCHEMBL514682 | 0.82 | ERN1 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4CASP1 | |
| Hydrochloric Acid SCHEMBL27803975 | 0.81 | ERN1 (0.44) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 | |
| SCHEMBL347177 | 0.79 | ERN1 (0.43) | ALDH1A1HSD17B10HIF1ATDP1GAA | |
| SCHEMBL545879 | 0.78 | ERN1 (0.42) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 | |
| SCHEMBL547776 | 0.78 | ERN1 (0.42) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 | |
| SCHEMBL984194 | 0.78 | KMT2A (0.50) | ALDH1A1HSD17B10HIF1ATDP1GAA | |
| SCHEMBL39718 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 | |
| SCHEMBL29392367 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 | |
| SCHEMBL9851160 | 0.76 | TYMS (0.45) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044284-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| US-9831448-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-9831448-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20160233443-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160233443-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| WO-2015036074-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-03-19 | — | — | WO | disclosed |
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160233443-A1 | Metal Complexes | AP1M1, SOD1, AP3M1 | ALDH1A1 3771/4885HSD17B10 3051/4885HIF1A 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.