Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054343 | 1.00 | HTR6 (0.45) | HTR6L3MBTL1PLK1GABRA1GABRG2 | |
| SCHEMBL29957304 | 0.85 | HTR6 (0.46) | HTR6L3MBTL1GABRA1GABRG2GABRB3 | |
| SCHEMBL26204111 | 0.84 | HTR6 (0.45) | HTR6L3MBTL1ACHEMEN1KMT2A | |
| SCHEMBL2115428 | 0.84 | HTR6 (0.46) | HTR6L3MBTL1PLK1GABRA1GABRG2 | |
| SCHEMBL2461044 | 0.83 | ALDH1A1 (0.55) | HTR6L3MBTL1PLK1GABRA1GABRG2 | |
| SCHEMBL29954772 | 0.83 | AKR1C3 (0.46) | HTR6L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1778702 | 0.83 | AKR1C3 (0.46) | HTR6L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL3051164 | 0.83 | HTR6 (0.46) | HTR6L3MBTL1PLK1GABRA1GABRG2 | |
| SCHEMBL30407382 | 0.83 | HTR6 (0.46) | HTR6L3MBTL1PLK1GABRA1GABRG2 | |
| SCHEMBL16972300 | 0.83 | HTR6 (0.46) | HTR6L3MBTL1PLK1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |