Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778702 | 1.00 | AKR1C3 (0.46) | AKR1C3HTR6L3MBTL1AKR1C2PDE10A | |
| SCHEMBL29957304 | 0.84 | HTR6 (0.46) | HTR6L3MBTL1ALDH1A1STSKDM4E | |
| SCHEMBL18386657 | 0.84 | AKR1C3 (0.48) | AKR1C3HTR6L3MBTL1AKR1C2PDE10A | |
| SCHEMBL29443995 | 0.84 | ALDH1A1 (0.48) | AKR1C3HTR6AKR1C2PDE10AALDH1A1 | |
| SCHEMBL4376044 | 0.84 | ALDH1A1 (0.48) | AKR1C3HTR6AKR1C2PDE10AALDH1A1 | |
| SCHEMBL3054343 | 0.83 | HTR6 (0.45) | HTR6L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29992688 | 0.83 | AKR1C3 (0.47) | AKR1C3HTR6L3MBTL1AKR1C2PDE10A | |
| SCHEMBL29950705 | 0.83 | HTR6 (0.45) | HTR6L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29942639 | 0.83 | AKR1C3 (0.47) | AKR1C3HTR6L3MBTL1AKR1C2PDE10A | |
| SCHEMBL29992656 | 0.83 | AKR1C3 (0.47) | AKR1C3HTR6L3MBTL1AKR1C2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |