Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | USP4 | Q13107 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331363 | 0.81 | HDAC8 (0.43) | HDAC8MAPTPKMUSP4USP7 | |
| SCHEMBL15331955 | 0.78 | CA2 (0.42) | HDAC8PKMRXFP1MEN1KMT2A | |
| SCHEMBL15332388 | 0.76 | GRN (0.38) | HDAC8PKMKDM4EALOX15NPSR1 | |
| SCHEMBL22808237 | 0.72 | MAPT (0.50) | MAPTPKMUSP4USP7KDM4E | |
| SCHEMBL2361283 | 0.71 | CYP2C9 (0.51) | HDAC8PKMKDM4EMEN1KMT2A | |
| SCHEMBL16404147 | 0.71 | RAB9A (0.42) | MAPTKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15332233 | 0.70 | HDAC8 (0.39) | HDAC8MAPTPKMUSP4USP7 | |
| SCHEMBL7670820 | 0.67 | RAB9A (0.63) | SMN1; SMN2ALDH1A1RAB9AMEN1HTT | |
| SCHEMBL11063029 | 0.67 | CYP1A2 (0.55) | HDAC8PKMKDM4EMEN1KMT2A | |
| SCHEMBL5206489 | 0.67 | PKM (0.51) | HDAC8PKMKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |