Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591554 | 0.86 | POLB (0.57) | POLBKMT2AMEN1PTPN1MAOB | |
| SCHEMBL5476476 | 0.79 | KMT2A (0.45) | POLBKMT2AMEN1PTPN1MAOB | |
| SCHEMBL28569270 | 0.77 | POLB (0.62) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL31037935 | 0.77 | POLB (0.62) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL11510369 | 0.76 | MAOB (0.59) | POLBKMT2AMEN1PTPN1MAOB | |
| SCHEMBL11616224 | 0.75 | MAOB (0.56) | MAOBMCL1ALOX15ALOX12CYP19A1 | |
| SCHEMBL11622080 | 0.75 | MAOB (0.56) | POLBKMT2AMEN1MAOBALOX15 | |
| SCHEMBL11869359 | 0.74 | MAOB (0.68) | POLBMAOBALDH1A1MAPTKDM4E | |
| SCHEMBL21591539 | 0.74 | SMN1; SMN2 (0.59) | POLBMAOBALDH1A1MAPTHPGD | |
| SCHEMBL29950744 | 0.74 | PTPN1 (1.00) | POLBKMT2AMEN1PTPN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807264-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |
| US-3959480-A | Polycyclic gamma-pyrone-3-carboxaldehyde derivatives | WARNER-LAMBERT COMPANY (US) | 1976-05-25 | — | — | US | disclosed |