Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.33 |
| ▸ | SCN4A | P35499 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366465 | 0.83 | SCN9A (0.44) | SCN9ASCN5ACYP3A4CYP2C9 | |
| SCHEMBL29957240 | 0.83 | SCN9A (0.44) | SCN9ASCN5ACYP3A4CYP2C9 | |
| SCHEMBL16734396 | 0.81 | SLC13A5 (0.33) | MEN1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL18151379 | 0.80 | LRRK2 (0.30) | — | |
| SCHEMBL29956843 | 0.79 | PTGS1 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL29955940 | 0.78 | ENPP2 (0.36) | POLBHTTMAPT | |
| SCHEMBL3635036 | 0.78 | ENPP2 (0.36) | POLBHTTMAPT | |
| SCHEMBL17248008 | 0.78 | NOS3 (0.41) | LMNAMEN1POLBHTTKMT2A | |
| SCHEMBL29955190 | 0.77 | CA1 (0.35) | KMT2ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17432904 | 0.72 | MEN1 (0.36) | LMNAMEN1POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |