SCHEMBL29956843

SCHEMBL29956843

CCCOc1ncc(B(O)O)cc1C

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.31
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
GABRA2 P47869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955190 0.92 CA1 (0.35) KDM4ENPC1RAB9ALPLLIPG
SCHEMBL16734396 0.86 SLC13A5 (0.33) ALDH1A1LPLLIPG
SCHEMBL29955039 0.82 ENPP2 (0.34) ALDH1A1LPLLIPG
SCHEMBL3635036 0.79 ENPP2 (0.36) LPLLIPG
SCHEMBL29955940 0.79 ENPP2 (0.36) LPLLIPG
SCHEMBL29950796 0.79 LMNA (0.35) KDM4EALDH1A1
SCHEMBL2243051 0.75 THRA (0.38) PTGS1PTGS2KDM4EALDH1A1LPL
SCHEMBL31652221 0.75 ALDH1A1 (0.34) KDM4ENPC1ALDH1A1RAB9AGABRA1
SCHEMBL18151379 0.75 LRRK2 (0.30)
SCHEMBL29956760 0.74 BCHE (0.38) NPC1ALDH1A1RAB9ALPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed