Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 2/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15148294 | 0.86 | AADAT (0.43) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL31019700 | 0.84 | NPBWR1 (0.42) | ALDH1A1LMNAKDM4EL3MBTL1MAPT | |
| SCHEMBL964648 | 0.81 | KMT2A (0.60) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL29951608 | 0.79 | — | — | |
| SCHEMBL29951706 | 0.78 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL29951177 | 0.77 | KMT2A (0.46) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL29956092 | 0.77 | KMT2A (0.48) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL6417130 | 0.77 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL29958109 | 0.76 | KMT2A (0.45) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL25972149 | 0.76 | KMT2A (0.51) | KMT2AMEN1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |