Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | IDE | P14735 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956317 | 0.87 | ALDH1A1 (0.69) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL29951078 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL29953314 | 0.83 | ALDH1A1 (0.63) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL7653003 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL29953285 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL29951512 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL29955092 | 0.73 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1GAAMAPTMEN1 | |
| SCHEMBL29957848 | 0.71 | GAA (0.53) | ALDH1A1HTTL3MBTL1GAAMAPT | |
| SCHEMBL29951452 | 0.70 | RAB9A (0.35) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL29952488 | 0.69 | ALDH1A1 (0.55) | ALDH1A1HTTL3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |