Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | HTT | P42858 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | IDE | P14735 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955058 | 0.85 | GAA (0.49) | ALDH1A1HTTL3MBTL1MAPTMEN1 | |
| SCHEMBL29956317 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HTTL3MBTL1MAPTMEN1 | |
| SCHEMBL29950834 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HTTL3MBTL1MAPTMEN1 | |
| SCHEMBL7653003 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HTTL3MBTL1MAPTMEN1 | |
| SCHEMBL29952095 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL29953285 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HTTL3MBTL1MAPTMEN1 | |
| SCHEMBL29953981 | 0.71 | MEN1 (0.43) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL15330010 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HTTL3MBTL1MAPTMEN1 | |
| SCHEMBL29951078 | 0.69 | ALDH1A1 (0.50) | ALDH1A1HTTL3MBTL1MAPTMEN1 | |
| SCHEMBL29957848 | 0.69 | GAA (0.53) | ALDH1A1HTTL3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |