Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951679 | 0.89 | HPGD (0.50) | ALDH1A1HPGDL3MBTL1LDHASMN1; SMN2 | |
| SCHEMBL29951179 | 0.88 | MAPT (0.49) | ALDH1A1HPGDL3MBTL1SRCCYP1A2 | |
| SCHEMBL29955253 | 0.83 | HPGD (0.59) | ALDH1A1HPGDL3MBTL1SRCNPC1 | |
| SCHEMBL20150988 | 0.83 | SRC (0.56) | ALDH1A1HPGDSRCCYP1A2CYP2C19 | |
| SCHEMBL2555240 | 0.83 | SRC (0.56) | ALDH1A1HPGDSRCSMN1; SMN2CYP1A2 | |
| SCHEMBL15330673 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL29952949 | 0.82 | HPGD (0.66) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL29952197 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDSRCSMN1; SMN2TSHR | |
| SCHEMBL2558374 | 0.81 | ALDH1A1 (0.57) | ALDH1A1HPGDL3MBTL1LDHASMN1; SMN2 | |
| SCHEMBL2555444 | 0.80 | SRC (0.52) | ALDH1A1HPGDSRCSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |