Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ATF4 | P18848 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956687 | 0.94 | HPGD (0.67) | HPGDSMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL29952732 | 0.93 | ALDH1A1 (0.68) | HPGDSMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL2556239 | 0.91 | HPGD (0.55) | HPGDSMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL29957558 | 0.87 | HPGD (0.54) | HPGDSMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL29950864 | 0.82 | ALDH1A1 (0.57) | HPGDSMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL15332063 | 0.81 | SMN1; SMN2 (0.65) | HPGDSMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL2561106 | 0.81 | NPC1 (0.69) | HPGDSMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL29951679 | 0.81 | HPGD (0.50) | HPGDSMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL29952950 | 0.81 | HPGD (0.60) | HPGDSMN1; SMN2HTTLMNAPTGDR2 | |
| SCHEMBL29952717 | 0.79 | KDM4E (0.64) | HPGDSMN1; SMN2HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |