Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATF4 | P18848 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950864 | 0.89 | ALDH1A1 (0.57) | HPGDTSHRHSD17B10GAAALDH1A1 | |
| SCHEMBL2556276 | 0.84 | ALDH1A1 (0.44) | HPGDGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL2553617 | 0.83 | ALDH1A1 (0.47) | HPGDTSHRHSD17B10GAAALDH1A1 | |
| SCHEMBL15330673 | 0.81 | SMN1; SMN2 (0.54) | HPGDALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29952949 | 0.81 | HPGD (0.66) | HPGDTSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL15333167 | 0.81 | ALDH1A1 (0.48) | HPGDTSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL2557685 | 0.81 | SMN1; SMN2 (0.45) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL2561415 | 0.81 | SMN1; SMN2 (0.47) | GAAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL20150682 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL9248575 | 0.79 | PTGDR2 (0.60) | HPGDALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |