Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31581099 | 1.00 | LMNA (0.50) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3833569 | 0.83 | LMNA (0.49) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL4879136 | 0.80 | MAPT (0.47) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12932763 | 0.80 | ALDH1A1 (0.55) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL17204103 | 0.77 | PIK3CG (0.50) | ALDH1A1MAPK1PIK3CDPIK3CG | |
| SCHEMBL1369496 | 0.77 | LMNA (0.53) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL17132665 | 0.76 | LMNA (0.49) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2323303 | 0.76 | ENPP2 (0.55) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL520205 | 0.75 | MAPT (0.65) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16599379 | 0.75 | CA12 (0.60) | LMNASMN1; SMN2KMT2ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |