Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011536 | 0.84 | VCAM1 (0.61) | MAPTVCAM1MEN1KMT2AALDH1A1 | |
| SCHEMBL16004920 | 0.82 | CA12 (0.64) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL11566829 | 0.82 | CRHBP (0.60) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL10946461 | 0.81 | CRHBP (0.73) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL1761873 | 0.81 | VCAM1 (0.62) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL4004897 | 0.80 | KMT2A (0.62) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL29952953 | 0.80 | KMT2A (0.62) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL6113956 | 0.80 | PDK1 (0.69) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL19306354 | 0.79 | TSHR (0.62) | CRHBPCRHR2CA12CA1CA2 | |
| SCHEMBL13977122 | 0.79 | MAPT (0.52) | MAPTVCAM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |