SCHEMBL29950985

SCHEMBL29950985

Cc1cc(B(O)O)c2ccccc2n1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.62
NCF1 P14598 5/20 0.58
L3MBTL1 Q9Y468 2/20 0.49
HTT P42858 2/20 0.49
ADRB2 P07550 1/20 0.49
ADRB1 P08588 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GALR3 O60755 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GPR3 P46089 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955591 0.80 MAOA (0.43) CYP1A2NCF1L3MBTL1MEN1KMT2A
SCHEMBL16010147 0.79 NCF1 (0.45) CYP1A2NCF1L3MBTL1HTTADRB2
SCHEMBL29955050 0.78 ALDH1A1 (0.49) CYP1A2NCF1MEN1KMT2AALDH1A1
SCHEMBL2652276 0.78 ALDH1A1 (0.49) CYP1A2NCF1MEN1KMT2AALDH1A1
SCHEMBL26695128 0.78 BACE1 (0.61) CYP1A2NCF1KDM4EALDH1A1HPGD
SCHEMBL30199873 0.78 CYP1A2 (0.64) CYP1A2NCF1L3MBTL1HTTMEN1
SCHEMBL266459 0.78 CYP1A2 (0.64) CYP1A2NCF1L3MBTL1HTTMEN1
Water SCHEMBL29955616 0.77 ALDH1A1 (0.47) CYP1A2NCF1MEN1KMT2AALDH1A1
SCHEMBL29502790 0.77 CYP1A2 (1.00) CYP1A2NCF1L3MBTL1KMT2ACYP2C19
SCHEMBL89010 0.77 CYP1A2 (1.00) CYP1A2NCF1L3MBTL1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed