Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677307 | 0.80 | MEN1 (0.47) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL8163931 | 0.80 | MEN1 (0.34) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL31522712 | 0.75 | MAOA (0.47) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL28878339 | 0.75 | MEN1 (0.46) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL29956246 | 0.75 | MEN1 (0.42) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL9142803 | 0.75 | MAOA (0.47) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL7503502 | 0.74 | MEN1 (0.44) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL29915861 | 0.74 | MEN1 (0.44) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL208852 | 0.74 | MEN1 (0.44) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL12203852 | 0.71 | OPRM1 (0.46) | MEN1KMT2AGAAALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |