Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666301 | 0.90 | PARP10 (0.44) | PARP10PARP1TDP1L3MBTL1TDP2 | |
| SCHEMBL15173274 | 0.87 | SRD5A1 (0.45) | PARP10PARP1TDP1L3MBTL1TDP2 | |
| SCHEMBL30856147 | 0.83 | TDP1 (0.49) | PARP10PARP1TDP1L3MBTL1TDP2 | |
| SCHEMBL10531263 | 0.80 | PARP1 (0.46) | PARP10PARP1TDP1L3MBTL1TDP2 | |
| SCHEMBL29953520 | 0.76 | MAOA (0.47) | MAOAMAOBMETAP1 | |
| SCHEMBL6832547 | 0.76 | MAOA (0.47) | MAOAMAOBMETAP1 | |
| SCHEMBL29952458 | 0.75 | ESR1 (0.54) | PARP10PARP1TDP1L3MBTL1PARP11 | |
| SCHEMBL2063760 | 0.75 | ESR1 (0.54) | PARP10PARP1TDP1L3MBTL1PARP11 | |
| SCHEMBL988678 | 0.75 | LMNA (0.39) | MAOBERN1PBRM1 | |
| SCHEMBL449192 | 0.75 | MAOB (0.46) | MAOAMAOBPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |