Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832547 | 1.00 | MAOA (0.47) | MAOAMAOBCYP19A1CYP11B2NQO2 | |
| SCHEMBL29582798 | 0.88 | MIF (0.47) | CYP19A1CYP11B2ALDH1A1NPC1LMNA | |
| SCHEMBL448275 | 0.88 | MIF (0.47) | CYP19A1CYP11B2ALDH1A1NPC1LMNA | |
| SCHEMBL6831713 | 0.81 | FGF23 (0.45) | MAOAMAOBCYP19A1CYP11B2NQO2 | |
| SCHEMBL6831715 | 0.81 | FGF23 (0.45) | MAOAMAOBCYP19A1CYP11B2NQO2 | |
| SCHEMBL28348471 | 0.78 | MAOB (0.46) | MAOAMAOBCYP19A1CYP11B2NQO2 | |
| SCHEMBL15333322 | 0.78 | PDE4D (0.43) | MAOAMAOBCYP19A1CYP11B2ALDH1A1 | |
| SCHEMBL29951071 | 0.76 | PARP10 (0.46) | MAOAMAOBMETAP1 | |
| SCHEMBL10531263 | 0.76 | PARP1 (0.46) | CYP19A1CYP11B2MAPK14ACHE | |
| SCHEMBL316466 | 0.74 | CYP26A1 (0.48) | CYP19A1CYP11B2ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |