Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559592 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4ERAB9AP2RY14CYP1A2 | |
| SCHEMBL2556140 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL29954369 | 0.83 | MAOA (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6538870 | 0.83 | RAB9A (0.63) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL2555132 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL4489356 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2P2RY14LMNA | |
| SCHEMBL2556056 | 0.79 | ALDH1A1 (0.82) | ALDH1A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL2558600 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL29953109 | 0.79 | ALDH1A1 (0.75) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL15331959 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |