SCHEMBL29951089

SCHEMBL29951089

CCOc1ccnc(C=O)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.43
HPGD P15428 2/20 0.43
LMNA P02545 3/20 0.42
ALDH1A1 P00352 9/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TACR2 P21452 1/20 0.36
IKBKB O14920 1/20 0.35
AOC3 Q16853 1/20 0.34
MAPK1 P28482 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP3A4 P08684 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27861568 0.86 MAPT (0.38) SMN1; SMN2HPGDALDH1A1L3MBTL1TDP1
SCHEMBL27844295 0.83 GAA (0.38) LMNAALDH1A1L3MBTL1TDP1MAPT
SCHEMBL29935924 0.81 ALDH1A1 (0.37) HPGDALDH1A1TDP1MAPTTSHR
SCHEMBL934218 0.76 GRM5 (0.45) LMNAALDH1A1L3MBTL1MAPTNPSR1
SCHEMBL28133216 0.76 NOS3 (0.33)
SCHEMBL16727177 0.75 HPGD (0.50) SMN1; SMN2HPGDLMNAALDH1A1L3MBTL1
SCHEMBL4080885 0.73 HPGD (0.63) SMN1; SMN2HPGDLMNAALDH1A1L3MBTL1
SCHEMBL2085241 0.72 NOS2 (0.46) LMNAALDH1A1TSHR
SCHEMBL2454114 0.71 ALDH1A1 (0.37) SMN1; SMN2HPGDLMNAALDH1A1L3MBTL1
SCHEMBL22333151 0.69 DAO (0.32) HPGDLMNAALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed