Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955920 | 0.88 | CSNK2A1 (0.54) | CSNK2A1POLBLOXLOXL2IKBKB | |
| SCHEMBL29952250 | 0.79 | POLB (0.40) | CSNK2A1POLBALDH1A1L3MBTL1GAA | |
| SCHEMBL14327024 | 0.77 | ALDH1A1 (0.58) | POLBALDH1A1L3MBTL1TDP1HPGD | |
| SCHEMBL24190659 | 0.76 | TDP1 (0.48) | POLBTDP1 | |
| SCHEMBL29333351 | 0.76 | POLB (0.47) | POLBALDH1A1 | |
| SCHEMBL30396359 | 0.76 | TDP1 (0.48) | POLBTDP1 | |
| SCHEMBL29956602 | 0.74 | PARP10 (0.50) | PDE4B | |
| SCHEMBL29956019 | 0.73 | POLB (0.42) | CSNK2A1POLBLOXLOXL2PDE4B | |
| SCHEMBL29951528 | 0.73 | POLB (0.39) | CSNK2A1POLBLOXLOXL2IKBKB | |
| SCHEMBL29957981 | 0.72 | HPGD (0.40) | CSNK2A1POLBALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |