Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648162 | 1.00 | LIPE (0.58) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL2558821 | 0.84 | LIPE (0.53) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL21352401 | 0.83 | LIPE (0.56) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL29955137 | 0.82 | LIPE (0.40) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL21352402 | 0.81 | ENPP2 (0.55) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL17825551 | 0.81 | LIPE (0.54) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL384778 | 0.81 | HTT (0.55) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL2559964 | 0.81 | LIPE (0.50) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL4334443 | 0.81 | ALDH1A1 (0.55) | HTR2CTLR8ALDH1A1GAACYP1A2 | |
| SCHEMBL2553619 | 0.79 | ALDH1A1 (0.44) | LIPETLR8ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |