Benzene

Benzene

SCHEMBL2995124

CCCCc1cccc(C)c1OC.c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
PPARA Q07869 2/20 0.44
PTGER4 P35408 2/20 0.43
PTGER3 P43115 2/20 0.43
PTGER2 P43116 2/20 0.43
PTGER1 P34995 1/20 0.43
LIPG Q9Y5X9 1/20 0.40
TLR8 Q9NR97 1/20 0.39
SCN8A Q9UQD0 1/20 0.39
CYSLTR2 Q9NS75 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38
BID P55957 3/20 0.37
MCL1 Q07820 3/20 0.37
BCL2L1 Q07817 2/20 0.37
BAK1 Q16611 2/20 0.37
KAT8 Q9H7Z6 2/20 0.37
PPARG P37231 1/20 0.37
EP300 Q09472 1/20 0.37
KAT2A Q92830 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6763527 0.98 ALOX5 (0.47) ALOX5PTGS2PPARAPTGER4PTGER3
SCHEMBL16959188 0.87 SCN8A (0.39) ALOX5PTGS2PTGER4PTGER3PTGER2
SCHEMBL16829571 0.87 ALOX5 (0.53) ALOX5PTGS2PPARALIPGBID
SCHEMBL20534823 0.85 LIPG (0.42) ALOX5PTGS2PPARAPTGER4PTGER3
SCHEMBL6304044 0.82 LIPG (0.43) ALOX5PTGS2PPARAPTGER4PTGER3
SCHEMBL23964582 0.82 PTGER4 (0.43) ALOX5PTGS2PPARAPTGER4PTGER3
SCHEMBL11100289 0.82 PTGER4 (0.40) ALOX5PTGS2PTGER4PTGER3PTGER2
SCHEMBL27456561 0.81 PTPN1 (0.47) ALOX5PTGS2PPARAPTGER4PTGER3
SCHEMBL16791967 0.81 PTGER4 (0.42) ALOX5PTGS2PPARAPTGER4PTGER3
SCHEMBL19451864 0.80 PTGER4 (0.58) PPARAPTGER4PTGER3PTGER2PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2185125-B1 COSMETIC EMULSIFIER COMBINATION BEIERSDORF AG (DE) 2018-02-21 EP claimed
US-20230121157-A1 ANTI-AGING CARE COMPOSITION COMPRISING PERFUMES BASF SE (DE) 2023-04-20 US disclosed
US-20140140940-A1 Cosmetic And Dermatological Photoprotective Preparation With Improved Water Resistance BEIERSDORF AG (DE) 2014-05-22 US disclosed
US-20100189755-A1 Dryer Sheets and a Method for Treating Skin COGNIS IP MANAGEMENT GMBH (DE) 2010-07-29 US disclosed
EP-1640042-B1 Cosmetic skin-whitening and cleansing composition comprising extracts from lotus, kiwi, orchids and liquorice COTY PRESTIGE LANCASTER GROUP (DE) 2009-12-30 EP disclosed
EP-1746972-A1 COSMETIC METHOD FOR TREATING SKIN WITH SUN PRODUCTS AND SUN PRODUCT COMBINATION Coty B.V. (NL) 2007-01-31 EP disclosed
EP-1640042-A1 Cosmetic skin-whitening and cleansing composition comprising extracts from lotus, kiwi, orchids and liquorice Lancaster Group GmbH (DE) 2006-03-29 EP disclosed
WO-2005102260-A1 COSMETIC METHOD FOR TREATING SKIN WITH SUN PRODUCTS AND SUN PRODUCT COMBINATION COTY B.V. (NL) 2005-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230121157-A1 ANTI-AGING CARE COMPOSITION COMPRISING PERFUMES CUTA, GLA, DPY30 ALOX5 172/4885PTGS2 2745/4885PPARA 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.