SCHEMBL29951297

SCHEMBL29951297

OB(O)c1ccn(CC2CC2)c1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CYP2B6 P20813 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950823 0.72 LPL (0.40) CA1CA2
SCHEMBL28839535 0.71 CA12 (0.47) CA12CA1CA2CA9CYP2B6
SCHEMBL17522927 0.70 DPP4 (0.33) CA12CA1CA2CA9
SCHEMBL2555775 0.68 CA12 (0.33) CA12CA1CA2CA9
SCHEMBL2560987 0.68
SCHEMBL29954474 0.67 CYP2C19 (0.47) CA12CA1CA2CA9
SCHEMBL29951986 0.66 WDR5 (0.33) CA12CA1CA2CA9
SCHEMBL21602961 0.66 PIK3CD (0.37)
SCHEMBL15332412 0.66 ENPP2 (0.34) CA1CA2
SCHEMBL29953396 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed