SCHEMBL2995133

SCHEMBL2995133

CCC1(C)CC(=O)NC(C)C(C)(CC)N1[O]

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
CYP2C19 P33261 1/20 0.35
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14300463 0.84 KDM4E (0.35) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL5325495 0.84 KDM4E (0.35) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL7071595 0.83 KDM4E (0.34) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL265092 0.75 KDM4E (0.31) KDM4ELMNACYP2C19
SCHEMBL4951959 0.71
SCHEMBL27391947 0.67 KDM4E (0.36) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL11459912 0.67 KDM4E (0.37) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL6278690 0.67 KDM4E (0.38) KDM4ELMNACYP2C19TSHRNPSR1
SCHEMBL16097822 0.66
SCHEMBL265670 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100143805-A1 NITROXIDES FOR LITHIUM-ION BATTERIES CIBA CORPORATION (NY) 2010-06-10 US disclosed
EP-2122739-A1 NITROXIDES FOR LITHIUM-ION BATTERIES BASF SE (DE) 2009-11-25 EP disclosed
WO-2008110466-A1 NITROXIDES FOR LITHIUM-ION BATTERIES BASF SE (CH) 2008-09-18 WO disclosed
EP-1873199-A1 In-can stabilizers Ciba Specialty Chemicals Holding Inc. (CH) 2008-01-02 EP disclosed
US-20070225397-A1 In-Can Stabilizers CIBA SPECIALTY CHEMICALS CORP. 2007-09-27 US disclosed
US-6664353-B2 Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-16 US disclosed
US-20030125494-A1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes NESVADBA PETER (CH) 2003-07-03 US disclosed
US-6479608-B1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143805-A1 NITROXIDES FOR LITHIUM-ION BATTERIES OGG1, NOX4, NQO1 KDM4E 1577/4885LMNA 3103/4885CYP2C19 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.