SCHEMBL265092

SCHEMBL265092

CCC1(C)CC(=O)C(C)C(C)(CC)N1[O]

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
CYP2C19 P33261 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13050901 0.82 KDM4E (0.31) KDM4ELMNACYP2C19MAPT
SCHEMBL265093 0.81
SCHEMBL15070005 0.78 MAPT (0.32) MAPT
SCHEMBL12557565 0.78
SCHEMBL13009033 0.78 KDM4E (0.32) KDM4ELMNACYP2C19
SCHEMBL4951959 0.75
SCHEMBL2995133 0.75 KDM4E (0.35) KDM4ELMNACYP2C19
SCHEMBL13008722 0.74
SCHEMBL4799883 0.74
SCHEMBL1138284 0.73 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1786860-B1 IN-CAN STABILIZERS CIBA SC HOLDING AG (CH) 2008-03-26 EP claimed
US-6927295-B2 A polymerization catalyst for free radical polymerization of ethylenically unsaturated monomers CIBA SPECIALTY CHEMICALS CORP. (US) 2005-08-09 US claimed
US-10316114-B2 End-functionalized polymers BASF SE (DE) 2019-06-11 US disclosed
EP-2552971-B1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2014-07-02 EP disclosed
EP-1606259-B1 PROCESS FOR THE OXIDATION OF SECONDARY AMINES INTO THE CORRESPONDING NITROXIDES BASF SE (DE) 2014-06-25 EP disclosed
EP-2552971-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2013-02-06 EP disclosed
US-20130030071-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2013-01-31 US disclosed
US-8134009-B2 Process for the oxidation of secondary amines into the corresponding nitroxides BASF SE (DE) 2012-03-13 US disclosed
US-20110319535-A1 IN-CAN STABILIZERS NESVADBA PETER (CH) 2011-12-29 US disclosed
WO-2011120947-A1 END-FUNCTIONALIZED POLYMERS BASF SE (DE) 2011-10-06 WO disclosed
US-20100305322-A1 Process for the Oxidation of Secondary Amines into the Corresponding Nitroxides CIBA SPECIALTY CHEMICALS CORPORATION 2010-12-02 US disclosed
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (SE) 2005-06-16 US disclosed
WO-2004085397-A1 PROCESS FOR THE OXIDATION OF SECONDARY AMINES INTO THE CORRESPONDING NITROXIDES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-10-07 WO disclosed
US-20040167303-A1 Multifunctional alkoxyamines based on polyalkylpiperidines, polyalkylpiperazinones and polyalkylmorpholinones and their use as polymerization regulators/initiators CIBA SPECIALTY CHEMICALS CORP. 2004-08-26 US disclosed
EP-1417171-A1 MULTIFUNCTIONAL ALKOXYAMINES BASED ON POLYALKYLPIPERIDINES, POLYALKYLPIPERAZINONES AND POLYALKYLMORPHOLINONES AND THEIR USE AS POLYMERIZATION REGULATORS/INITIATORS Ciba SC Holding AG (CH) 2004-05-12 EP disclosed
US-6683142-B2 PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-27 US disclosed
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2003-11-27 US disclosed
WO-2003004471-A1 MULTIFUNCTIONAL ALKOXYAMINES BASED ON POLYALKYLPIPERIDINES, POLYALKYLPIPERAZINONES AND POLYALKYLMORPHOLINONES AND THEIR USE AS POLYMERIZATION REGULATORS/INITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-01-16 WO disclosed
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2002-08-08 US disclosed
US-6353107-B1 FREE RADICAL CATALYSTS FOR ADDITION POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTION; HIGH PURITY AND COLORLESS CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305322-A1 Process for the Oxidation of Secondary Amines into the Corresponding Nitroxides NOS2, NOS1, NOS3 KDM4E 1511/4885LMNA 2339/4885CYP2C19 301/4885
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, PTGER1, CBR1 KDM4E 1318/4885LMNA 213/4885CYP2C19 1143/4885
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CBR1, PYM1, ELOC KDM4E 2651/4885LMNA 156/4885CYP2C19 1389/4885
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, ELOC, CBR1 KDM4E 2507/4885LMNA 147/4885CYP2C19 1307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.