Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954149 | 0.79 | CDK1 (0.48) | PNPLMNAMAPTCDK1CDK4 | |
| SCHEMBL13022826 | 0.74 | PNP (0.46) | PNPXDHTYMSLMNAMAPT | |
| SCHEMBL29954039 | 0.72 | PNP (0.32) | PNPXDHTYMSLMNA | |
| SCHEMBL192661 | 0.71 | LMNA (0.55) | LMNAMAPTNPSR1RECQL | |
| SCHEMBL4572376 | 0.68 | CDK1 (0.66) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL29952359 | 0.67 | PNP (0.34) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL6441238 | 0.67 | XDH (0.53) | PNPXDHLMNAMAPTCDK1 | |
| SCHEMBL6364307 | 0.66 | LMNA (0.50) | LMNAMAPTNPSR1RECQL | |
| SCHEMBL727348 | 0.65 | TYMS (0.44) | PNPXDHTYMS | |
| SCHEMBL29950870 | 0.64 | LMNA (0.41) | LMNAMAPTALOX15NPSR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |