Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561948 | 0.77 | MAP4K4 (0.54) | ALDH1A1L3MBTL1MAP4K4 | |
| SCHEMBL2554450 | 0.76 | PTPN11 (0.39) | PIK3CA | |
| SCHEMBL2554196 | 0.76 | USP7 (0.41) | ALDH1A1L3MBTL1MAP4K4 | |
| SCHEMBL2558901 | 0.73 | CHEK2 (0.53) | MAP4K4 | |
| SCHEMBL29951522 | 0.72 | MAP4K4 (0.51) | MAP4K4 | |
| SCHEMBL29951774 | 0.71 | CHEK2 (0.51) | PIK3CAMAP4K4 | |
| SCHEMBL2557950 | 0.70 | MAP4K4 (0.56) | PIK3CAALDH1A1L3MBTL1MAP4K4 | |
| SCHEMBL15333189 | 0.69 | ATR (0.42) | ALDH1A1 | |
| SCHEMBL29955230 | 0.69 | ALOX5AP (0.38) | — | |
| SCHEMBL29955302 | 0.69 | ERN1 (0.34) | VRK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |