SCHEMBL29951489

SCHEMBL29951489

OB(O)c1cc2ccccc2cc1OC(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ENPP2 Q13822 1/20 0.38
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
TSHR P16473 2/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
NQO1 P15559 1/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952051 0.79 ENPP2 (0.57) CA1CA2ENPP2HPGDKDM4E
SCHEMBL29469117 0.79 ENPP2 (0.57) ENPP2ALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL14746822 0.79 ENPP2 (0.57) ENPP2ALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL2202666 0.79 ENPP2 (0.57) CA1CA2ENPP2HPGDKDM4E
SCHEMBL29957321 0.77 NPC1 (0.37) CA1CA2ALDH1A1TSHRMAPT
SCHEMBL29952553 0.76 CA1 (0.37) CA1CA2ENPP2HPGDKDM4E
SCHEMBL29953320 0.75 ENPP2 (0.40) ENPP2ALDH1A1L3MBTL1MAPTKMT2A
SCHEMBL30944694 0.75 CA1 (0.54) CA1CA2ENPP2KDM4EMAPT
SCHEMBL29952656 0.74 HTT (0.36) ENPP2HPGDALDH1A1L3MBTL1MAPT
SCHEMBL15010805 0.74 HTT (0.36) ENPP2HPGDALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed