SCHEMBL29957321

SCHEMBL29957321

OB(O)c1cc(OC(F)F)cc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GRM2 Q14416 1/20 0.36
MAPT P10636 3/20 0.35
TSHR P16473 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CDC25B P30305 1/20 0.33
HTT P42858 1/20 0.33
PPARG P37231 3/20 0.33
PPARA Q07869 3/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
ERN1 O75460 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TRPM4 Q8TD43 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952009 0.84 MAPT (0.37) NPC1RAB9AMEN1KMT2AGRM2
SCHEMBL2201994 0.79 CDC25B (0.50) MAPTCA1CA2CDC25BERN1
SCHEMBL29955307 0.79 CDC25B (0.50) MAPTCA1CA2CDC25BERN1
SCHEMBL29469023 0.79 CDC25B (0.50) MAPTCA1CA2CDC25BERN1
SCHEMBL29951489 0.77 IRAK4 (0.39) RAB9AMEN1KMT2AMAPTTSHR
SCHEMBL21822095 0.77 GRM2 (0.39) NPC1RAB9AMEN1KMT2AGRM2
SCHEMBL29951136 0.77 ACP1 (0.41) CA1CA2CDC25BERN1
SCHEMBL4080396 0.75 L3MBTL1 (0.41) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL29954014 0.74 MTNR1A (0.40) NPC1RAB9AMEN1KMT2AGRM2
SCHEMBL29951631 0.74 TRPM4 (0.39) MEN1KMT2AMAPTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed