Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15010805 | 1.00 | HTT (0.36) | HTTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL29956495 | 0.87 | ENPP2 (0.39) | HTTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL264985 | 0.85 | ACLY (0.39) | KMT2AALDH1A1MEN1MAPTKCNH2 | |
| SCHEMBL6460545 | 0.82 | ENPP2 (0.36) | KMT2AMEN1MAPTENPP2L3MBTL1 | |
| SCHEMBL29956290 | 0.81 | ALDH1A1 (0.49) | HTTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL29957287 | 0.80 | MCHR1 (0.36) | KMT2AMEN1MAPTL3MBTL1HPGD | |
| SCHEMBL4572 | 0.79 | ENPP2 (0.57) | HTTSMN1; SMN2ENPP2TUBB4ATUBB | |
| SCHEMBL31040152 | 0.79 | ENPP2 (0.57) | HTTSMN1; SMN2ENPP2TUBB4ATUBB | |
| SCHEMBL29469117 | 0.79 | ENPP2 (0.57) | HTTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL14746822 | 0.79 | ENPP2 (0.57) | HTTSMN1; SMN2KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |