Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955009 | 0.85 | PARP1 (0.42) | TLR8MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL29778037 | 0.80 | FERMT2 (0.45) | MEN1KMT2AKDR | |
| SCHEMBL28856475 | 0.80 | ALK (0.46) | ALDH1A1RIPK2KDM4ESMN1; SMN2 | |
| SCHEMBL29957635 | 0.80 | NR4A2 (0.56) | TLR8MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL29956653 | 0.78 | MEN1 (0.47) | TLR8MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL29952206 | 0.77 | HTR1A (0.55) | TLR8GAARIPK2KDM4ELMNA | |
| SCHEMBL4378078 | 0.77 | TLR8 (0.59) | TLR8MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL29509132 | 0.76 | TLR8 (0.54) | TLR8MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL28164080 | 0.76 | TLR8 (0.54) | TLR8MEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL31463020 | 0.76 | ALK (0.50) | PKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |