Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.56 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CHKA | P35790 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778053 | 0.87 | NR4A2 (0.58) | NR4A2SOS2LMNASMN1; SMN2PKM | |
| SCHEMBL29951591 | 0.80 | TLR8 (0.49) | LMNASMN1; SMN2ALOX15CASP1HSD17B10 | |
| SCHEMBL783960 | 0.79 | LMNA (0.44) | NR4A2SOS2LMNASMN1; SMN2PKM | |
| SCHEMBL28856475 | 0.79 | ALK (0.46) | SMN1; SMN2CYP1A2ALDH1A1NCF1KDM4E | |
| SCHEMBL29778037 | 0.79 | FERMT2 (0.45) | MAPK1KMT2AMEN1 | |
| SCHEMBL29952206 | 0.76 | HTR1A (0.55) | LMNACYP1A2TLR8MAPK1GAA | |
| SCHEMBL409748 | 0.76 | NR4A2 (0.61) | NR4A2SOS2PKMALOX15CASP1 | |
| SCHEMBL30772330 | 0.76 | NR4A2 (0.61) | NR4A2SOS2PKMALOX15CASP1 | |
| SCHEMBL2710661 | 0.76 | NR4A2 (0.61) | NR4A2SOS2LMNASMN1; SMN2PKM | |
| SCHEMBL29491409 | 0.76 | NR4A2 (0.61) | NR4A2SOS2LMNASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |