Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 3/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | STK16 | O75716 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856552 | 0.86 | SLC22A12 (0.49) | ALKGAKSLC22A12HTTCYP1A2 | |
| SCHEMBL29951591 | 0.80 | TLR8 (0.49) | KDM4EALDH1A1SMN1; SMN2RIPK2 | |
| SCHEMBL29957635 | 0.79 | NR4A2 (0.56) | CYP1A2NCF1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29778037 | 0.79 | FERMT2 (0.45) | GAKMPOACVR1AAK1 | |
| SCHEMBL29952206 | 0.76 | HTR1A (0.55) | GAKCYP1A2NCF1KDM4ERIPK2 | |
| SCHEMBL1490718 | 0.76 | ALK (0.50) | ALKGAKSLC22A12HTTCYP1A2 | |
| SCHEMBL30390607 | 0.76 | ALK (0.50) | ALKGAKSLC22A12HTTCYP1A2 | |
| SCHEMBL1496382 | 0.76 | ALK (0.50) | ALKGAKSLC22A12HTTCYP1A2 | |
| SCHEMBL29896720 | 0.75 | ALK (0.53) | ALKGAKSLC22A12HTTCYP1A2 | |
| SCHEMBL4470963 | 0.75 | ALK (0.53) | ALKGAKSLC22A12HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |