Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707502 | 0.83 | SCN8A (0.44) | SCN8AARSCN4ALMNASCN1A | |
| SCHEMBL29951567 | 0.83 | CA1 (0.37) | SCN8AENPP2LMNACYP3A4TRPA1 | |
| SCHEMBL2442618 | 0.81 | TRPV1 (0.34) | SCN8AENPP2 | |
| SCHEMBL29700387 | 0.81 | TRPV1 (0.34) | SCN8AENPP2 | |
| SCHEMBL29951401 | 0.80 | ENPP2 (0.53) | ARENPP2LMNATSHRCYP3A4 | |
| SCHEMBL24181283 | 0.78 | TRPA1 (0.50) | SCN8AARSCN4ALMNASCN1A | |
| SCHEMBL29956737 | 0.77 | ENPP2 (0.48) | ENPP2LMNACYP3A4KCNK3ALDH1A1 | |
| SCHEMBL16961246 | 0.76 | ACHE (0.44) | SCN8AARSCN4ALMNASCN1A | |
| SCHEMBL16952357 | 0.76 | S1PR1 (0.40) | SCN8AARSCN9AKCNK3SLC6A4 | |
| SCHEMBL16955011 | 0.76 | SCN8A (0.38) | SCN8AARSCN4ALMNASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |