Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947198 | 1.00 | CA2 (0.55) | CA2CA1TRPV1HIF1AALDH1A1 | |
| SCHEMBL21125905 | 0.80 | CA2 (0.41) | CA2CA1TRPV1HIF1AALDH1A1 | |
| SCHEMBL2644437 | 0.80 | MGLL (0.63) | CA2CA1MGLLENPP2MEN1 | |
| SCHEMBL29957058 | 0.80 | MGLL (0.63) | CA2CA1MGLLENPP2MEN1 | |
| SCHEMBL31354846 | 0.80 | CA2 (0.80) | CA2CA1ALDH1A1ENPP2LPL | |
| SCHEMBL205203 | 0.80 | CA2 (0.80) | CA2CA1ALDH1A1ENPP2LPL | |
| SCHEMBL30010382 | 0.80 | ALDH1A1 (0.52) | CA2CA1ALDH1A1HPGDALOX15 | |
| SCHEMBL348347 | 0.80 | ALDH1A1 (0.52) | CA2CA1ALDH1A1HPGDALOX15 | |
| SCHEMBL27736 | 0.78 | TRPV1 (0.66) | CA2CA1TRPV1MGLLENPP2 | |
| SCHEMBL28105147 | 0.78 | ALDH1A1 (0.50) | CA2CA1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |