Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96815 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL28083133 | 0.80 | MPL (0.45) | ALDH1A1GAAMPLKDM4EHCAR1 | |
| SCHEMBL2715747 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL16470387 | 0.80 | SRC (0.41) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL4628099 | 0.79 | LMNA (0.48) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL980265 | 0.79 | ERN1 (0.61) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL4115627 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL26812099 | 0.79 | ERN1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| SCHEMBL29732882 | 0.79 | ERN1 (0.61) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 | |
| Formaldehyde SCHEMBL27526817 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |