SCHEMBL980265

SCHEMBL980265

O=Cc1cccc(OC(F)(F)F)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 8/20 0.61
TLR2 O60603 1/20 0.61
TLR1 Q15399 1/20 0.61
TLR6 Q9Y2C9 1/20 0.61
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SRC P12931 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
CA12 O43570 1/20 0.39
GAA P10253 2/20 0.38
LMNA P02545 2/20 0.38
KMT2A Q03164 2/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732882 1.00 ERN1 (0.61) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL20108981 0.86 ERN1 (0.62) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL27934352 0.84 ERN1 (0.41) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL96815 0.81 ALDH1A1 (0.55) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL1044949 0.80 ALDH1A1 (0.39) ALDH1A1HPGDGAALMNAL3MBTL1
SCHEMBL16470387 0.80 SRC (0.41) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL2715747 0.80 ALDH1A1 (0.41) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL29951648 0.79 ALDH1A1 (0.40) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL4115627 0.79 ALDH1A1 (0.40) ERN1TLR2TLR1TLR6ALDH1A1
SCHEMBL26812099 0.79 ERN1 (0.47) ERN1TLR2TLR1TLR6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114634429-B Photosensitive diamine monomer and preparation method thereof, resin containing photosensitive diamine monomer and photosensitive resin composition 波米科技有限公司 2022-11-22 CN claimed
CN-114634429-A Photosensitive diamine monomer, preparation method thereof, resin containing photosensitive diamine monomer and photosensitive resin composition 波米科技有限公司 2022-06-17 CN claimed
EP-4703358-A1 BENZO SIX-MEMBERED HETEROCYCLIC GSPT1 PROTEIN DEGRADATION AGENT AND USE THEREOF China Pharmaceutical University (CN) 2026-03-04 EP disclosed
US-20250382312-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF BORAH INC (US) 2025-12-18 US disclosed
US-12404286-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof BORAH, INC. (US) 2025-09-02 US disclosed
WO-2025092775-A1 PHTHALAZINONE GSPT1 PROTEIN DEGRADING AGENT AND USE THEREOF 中国药科大学 2025-05-08 WO disclosed
CN-119912437-A Phthalazinone GSPT protein degradation agent and application thereof 中国药科大学 2025-05-02 CN disclosed
WO-2024222918-A1 BENZO SIX-MEMBERED HETEROCYCLIC GSPT1 PROTEIN DEGRADATION AGENT AND USE THEREOF 中国药科大学 2024-10-31 WO disclosed
US-20240352045-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2024-10-24 US disclosed
CN-117242080-A Boron-containing pyrazole compounds, compositions comprising the same, methods and uses thereof 勃林格殷格翰动物保健美国公司 2023-12-15 CN disclosed
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof Boehringer Ingelheim Animal Health USA Inc. (US) 2023-11-28 US disclosed
US-20110021522-A1 ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-27 US disclosed
EP-2237784-A1 ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 The Regents of the University of California (US) 2010-10-13 EP disclosed
US-20100093705-A1 Therapeutic agents, and methods of making and using the same DEBIOPHARM INTERNATIONAL SA (CH) 2010-04-15 US disclosed
US-20100093705-A1 Therapeutic agents, and methods of making and using the same DEBIOPHARM INTERNATIONAL SA (CH) 2010-04-15 US disclosed
US-20100093705-A1 Therapeutic agents, and methods of making and using the same DEBIOPHARM INTERNATIONAL SA (CH) 2010-04-15 US disclosed
WO-2009089508-A1 ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-07-16 WO disclosed
EP-1828167-A2 ACRYLAMIDE DERIVATIVES AS ANTIBIOTIC AGENTS Affinium Pharmaceuticals, Inc. (CA) 2007-09-05 EP disclosed
WO-2007053131-A2 ACRYLAMIDE DERIVATIVES AS ANTIBIOTIC AGENTS AFFINIUM PHARMACEUTICALS, INC. (CA) 2007-05-10 WO disclosed
US-20060142265-A1 Compositions comprising multiple bioactive agents, and methods of using the same AFFINIUM PHARMACEUTICALS, INC. (CA) 2006-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof JAK3, JAK1, JAK2 ERN1 1139/4885TLR2 1079/4885TLR1 443/4885
US-20250382312-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF JAK3, JAK1, JAK2 ERN1 1139/4885TLR2 1079/4885TLR1 443/4885
US-20100093705-A1 Therapeutic agents, and methods of making and using the same MCL1, DHFR, ANXA5 ERN1 2373/4885TLR2 1715/4885TLR1 1717/4885
US-20240352045-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF JAK3, JAK1, JAK2 ERN1 1139/4885TLR2 1079/4885TLR1 443/4885
US-20110021522-A1 ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 CASP7, CASP3, CASP6 ERN1 726/4885TLR2 4370/4885TLR1 3564/4885
US-20060142265-A1 Compositions comprising multiple bioactive agents, and methods of using the same DBI, SERPINB1, CTSF ERN1 1010/4885TLR2 2957/4885TLR1 3162/4885
US-12404286-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof JAK3, JAK1, JAK2 ERN1 1139/4885TLR2 1079/4885TLR1 443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.