Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950803 | 0.89 | POLB (0.37) | POLBMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL29956175 | 0.83 | POLB (0.36) | POLBMKNK1MKNK2 | |
| SCHEMBL29954303 | 0.80 | POLB (0.36) | POLB | |
| SCHEMBL29951714 | 0.80 | MKNK1 (0.44) | MKNK1MKNK2PDE4APDE4BPDE4C | |
| SCHEMBL29955165 | 0.77 | KMO (0.36) | POLBMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL29957238 | 0.77 | POLB (0.36) | POLB | |
| SCHEMBL29957106 | 0.76 | MKNK1 (0.43) | POLBMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL29953060 | 0.75 | POLB (0.37) | POLB | |
| SCHEMBL25213581 | 0.75 | FEN1 (0.36) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL22804596 | 0.75 | RIPK2 (0.34) | FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |