Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 6/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957290 | 0.88 | POLB (0.36) | KMOMKNK1MKNK2POLBGRIK1 | |
| SCHEMBL29951714 | 0.88 | MKNK1 (0.44) | MKNK1MKNK2PDE4APDE4BPDE4C | |
| SCHEMBL29955295 | 0.83 | KAT2B (0.44) | MKNK1MKNK2PDE4APDE4BPDE4C | |
| SCHEMBL29957106 | 0.81 | MKNK1 (0.43) | MKNK1MKNK2PDE4APDE4BPDE4C | |
| SCHEMBL25240993 | 0.79 | PDE4A (0.38) | KMOMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL25232405 | 0.79 | GABRP (0.39) | KMOMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL29951667 | 0.77 | POLB (0.36) | MKNK1MKNK2PDE4APDE4BPDE4C | |
| SCHEMBL29950803 | 0.75 | POLB (0.37) | MKNK1MKNK2PDE4APDE4BPDE4C | |
| SCHEMBL29955487 | 0.75 | KAT2B (0.44) | POLB | |
| SCHEMBL29957238 | 0.73 | POLB (0.36) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |