Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 4/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957238 | 0.90 | POLB (0.36) | POLBLRRK2RORCCSF1RTYK2 | |
| SCHEMBL29950803 | 0.80 | POLB (0.37) | POLB | |
| SCHEMBL29955487 | 0.79 | KAT2B (0.44) | POLBRORCTYK2 | |
| SCHEMBL29955295 | 0.76 | KAT2B (0.44) | POLBRORCTYK2 | |
| SCHEMBL29951667 | 0.75 | POLB (0.36) | POLB | |
| SCHEMBL73312 | 0.75 | PDE4B (0.46) | POLB | |
| SCHEMBL29955297 | 0.75 | POLB (0.42) | POLB | |
| SCHEMBL29954303 | 0.75 | POLB (0.36) | POLB | |
| SCHEMBL29957290 | 0.75 | POLB (0.36) | POLB | |
| SCHEMBL29953879 | 0.74 | ALDH1A1 (0.42) | POLBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |