SCHEMBL6419348

SCHEMBL6419348

O=C(O)c1ccc2c(C(=O)O)c[nH]c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.51
F3 P13726 1/20 0.51
SPR P35270 1/20 0.51
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
PTPN1 P18031 2/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP1A2 P05177 2/20 0.50
ENPP2 Q13822 1/20 0.50
MEN1 O00255 1/20 0.50
ALOX12 P18054 1/20 0.50
KMT2A Q03164 1/20 0.50
PRKAB2 O43741 2/20 0.47
PRKAG1 P54619 2/20 0.47
PRKAA2 P54646 2/20 0.47
PRKAA1 Q13131 2/20 0.47
PRKAG3 Q9UGI9 2/20 0.47
PRKAG2 Q9UGJ0 2/20 0.47
PRKAB1 Q9Y478 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17025018 0.90 PBRM1 (0.57) F7F3SPRALDH1A1HPGD
SCHEMBL29951669 0.90 PBRM1 (0.57) F7F3SPRALDH1A1HPGD
SCHEMBL1608195 0.90 ALDH1A1 (0.57) F7F3SPRALDH1A1HPGD
SCHEMBL18589525 0.90 CYP1A2 (0.64) ALDH1A1HPGDKDM4EHSD17B10CYP1A2
SCHEMBL6418497 0.85 NR4A2 (0.68) NR4A2TUBB1
SCHEMBL27853699 0.85 F7 (0.66) F7F3ALDH1A1HPGDPTPN1
SCHEMBL695797 0.84 KDM4E (0.48) SPRALDH1A1HPGDPTPN1KDM4E
SCHEMBL4780495 0.83 NPC1 (0.66) PARP1NR4A2TUBB1
SCHEMBL30899481 0.83 NPC1 (0.66) PARP1NR4A2TUBB1
SCHEMBL14142366 0.83 SPR (0.50) SPRALDH1A1HPGDPTPN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050178659-A1 Copolymer compound and electrochemical cell therewith NEC TOKIN CORPORATION (JP) 2005-08-18 US disclosed
EP-0774477-B1 Copolyesters and molded articles comprising the same KURARAY CO (JP) 2003-08-13 EP disclosed
US-5686553-A TEREPHTHALIC ACID AND ETHYLENE GLYCOL COMONOMERS; MOLDABILITY KURARAY CO., LTD. (JP) 1997-11-11 US disclosed
EP-0774477-A2 Copolyesters and molded articles comprising the same KURARAY CO., LTD. (JP) 1997-05-21 EP disclosed